| Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
| HGNC | UniGene | Nucleotide | OMIM | UCSC |
| Home Page |
| FLASH GENE |
| Symbol | MYL3 | contributors: - updated : 13-07-2006 |
| HGNC name | myosin, light polypeptide 3, alkali; ventricular, skeletal, slow |
| HGNC id | 7584 |
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| PROTEIN |
PHYSICAL PROPERTIES
| STRUCTURE
| |
motifs/domains
| three EF-hand domains |
| secondary structure | two heavy chains and four light chains |
| mono polymer | hexamer |
| HOMOLOGY |
| interspecies | homolog to murine Mylc |
| Homologene |
| FAMILY |
| CATEGORY | motor/contractile , structural protein |
SUBCELLULAR LOCALIZATION
| intracellular |
| intracellular,cytoplasm,cytoskeleton |
| basic FUNCTION | modulating the interaction between myosin and actin |
| CELLULAR PROCESS |
| PHYSIOLOGICAL PROCESS | cardiovascular |
| PATHWAY |
| metabolism |
| signaling |
| a component | myosin is an hexamer of 2 heavy chains and 4 light chains |
| INTERACTION |
| DNA |
| RNA |
| small molecule |
| protein | CASP3 (cleavage of MYL3 contributing to depression of myocyte function) |
| cell & other |
| REGULATION |
| ASSOCIATED DISORDERS |
| corresponding disease(s) | CMH8 |
| related resource | FHC Mutation Database |
| Susceptibility |
Variant & Polymorphism
|
Candidate gene
| Marker
| Therapy target
|
| |
| ANIMAL & CELL MODELS |