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FLASH GENE
Symbol MX1 contributors: mct - updated : 14-10-2009
HGNC name myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
HGNC id 7532
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --low  
in end-stage dilated cardiomyopathy
tumoral     --low  
by hypermethylation in head and neck tumors
constitutional     --other  
in multiple sclerosis, MX1 and MX2 proteins are detectable in plaques suggesting endogenous synthesis of type I IFNs as part of the acute inflammatory process
Susceptibility susceptibility factor for alopecia areata
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancermetastases 
its expression can be induced by small molecules, potentially offering a new approach to the prevention and treatment of metastasis
ANIMAL & CELL MODELS