Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol CPT2 contributors: npt/ - updated : 23-03-2007
HGNC name carnitine palmitoyltransferase II
HGNC id 2330
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal leader peptide 25 AA
  • carnitine O-acetyltransferase domain
    • HOMOLOGY
    interspecies ortholog to murine Cpt2
    Homologene
    FAMILY
  • carnitine/choline acetyltransferase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    basic FUNCTION
  • carnitine palmitoyltransferase, malonyl CoA insensitive involved in transesterification of lung and medium fatty acyl chains
  • converting palmitoylcarnitine into palmitoyl-CoA (palmitoyl-CoA shuttle system)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism lipid/lipoprotein
    signaling
    fatty acid beta oxidation pathway
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    inhibited by not inhibited by malonyl-CoA
    ASSOCIATED DISORDERS
    corresponding disease(s) CPT2 , CPT2I
    related resource MITOP database
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS