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FLASH GENE
Symbol CATSPER4 contributors: npt/ - updated : 21-09-2007
HGNC name cation channel, sperm associated 4
HGNC id 23220
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • coiled-coil protein-protein interaction domain in the C-terminal tail
  • a single-ion transport domain with six transmembrane spanning regions, in which the fourth transmembrane region resembles a voltage sensor and a pore-forming region lies between transmembrane regions 5 and 6
    • mono polymer heteromer , tetramer
    HOMOLOGY
    interspecies homolog to CATSPER1, CATSPER2
    Homologene
    FAMILY
  • Catsper family
  • cation channel sperm-associated family
    • CATEGORY receptor membrane
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • forms a hetero-tetrameric channel in sperm (in association with Catsper 1, 2, 3)
  • cation-channel protein having roles in acrosome reaction and male fertility
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS