Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

CATSPER4

contributors: npt/ - updated : 21-09-2007

HGNC name	cation channel, sperm associated 4
HGNC id	23220

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_198137 10 - 1419 NP_937770 - 472 - -

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive male system testis     specific

cells

System Cell Pubmed Species Stage Rna symbol Reproductive spermatid Reproductive spermatozoa

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	coiled-coil protein-protein interaction domain in the C-terminal tail
	a single-ion transport domain with six transmembrane spanning regions, in which the fourth transmembrane region resembles a voltage sensor and a pore-forming region lies between transmembrane regions 5 and 6

mono polymer

heteromer , tetramer

HOMOLOGY

interspecies

homolog to CATSPER1, CATSPER2

Homologene

FAMILY	Catsper family
	cation channel sperm-associated family

CATEGORY

receptor membrane

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION	forms a hetero-tetrameric channel in sperm (in association with Catsper 1, 2, 3)
	cation-channel protein having roles in acrosome reaction and male fertility

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS