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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

CXCL10

contributors: mct - updated : 22-01-2016

HGNC name	chemokine (C-X-C motif) ligand 10
HGNC id	10637

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in several neurodegenerative diseases, including multiple sclerosis, Alzheimer disease and HIV-associated dementia

Susceptibility

susceptibility to tuberculosis (TB)

Variant & Polymorphism SNP	new potential protective SNP (-135G>A) for TB is identified in the promoter of chemokine gene, CXCL-10

Candidate gene
Marker
Therapy target	targeting CXCL10 may provide a novel therapeutic means to ameliorate liver ischemia/reperfusion injury in clinics

ANIMAL & CELL MODELS