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FLASH GENE
Symbol DPEP3 contributors: mct - updated : 28-03-2019
HGNC name dipeptidase 3
HGNC id 23029
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemtestis    Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
secondary structure disulfide-linked
mono polymer homomer , dimer
HOMOLOGY
interspecies homolog to murine Dpep3
Homologene
FAMILY peptidase family M19
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     plasma membrane
text GPI-anchored
basic FUNCTION
  • hydrolyzes a wide range of dipeptides
  • implicated in the renal metabolism of glutathione and its conjugates
  • converts leukotriene d4 to leukotriene e4; it may play an important role in the regulation of leukotriene activity
  • cleaves cystinyl-bis-glycine but not LTD4
    • CELLULAR PROCESS protein, post translation
    protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor,
    zinc Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS