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FLASH GENE

Symbol

GRWD1

contributors: - updated : 25-06-2005

HGNC name	glutamate-rich WD repeat containing 1
HGNC id	21270

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine small intestine     highly Reproductive female system ovary     highly   female system uterus cervix   highly Skin/Tegument skin       highly Urinary kidney

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a glutamic/aspartic acid-rich domain of 14 consecutive AA from position 123 to 136
	four WD repeats

HOMOLOGY

interspecies

homolog to yeast Rrb1

Homologene

FAMILY

PSCD family

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm
	intracellular,nucleus,nucleolus

basic FUNCTION	ribosome assembly activity
	playing a role in ribosome biogenesis and regulated during myeloid differentiation

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

induced by

vitamin D3

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS