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FLASH GENE
Symbol GRWD1 contributors: - updated : 25-06-2005
HGNC name glutamate-rich WD repeat containing 1
HGNC id 21270
DNA
TYPE functioning gene
STRUCTURE 7.00 kb     7 Exon(s)
regulatory sequence Promoter
text structure 2 potential transcriptional regulatory regions in the promoter
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine  highly
Reproductivefemale systemovary  highly
 female systemuteruscervix highly
Skin/Tegumentskin   highly
Urinarykidney    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a glutamic/aspartic acid-rich domain of 14 consecutive AA from position 123 to 136
  • four WD repeats
    • HOMOLOGY
    interspecies homolog to yeast Rrb1
    Homologene
    FAMILY PSCD family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus,nucleolus
    basic FUNCTION
  • ribosome assembly activity
  • playing a role in ribosome biogenesis and regulated during myeloid differentiation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by vitamin D3
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS