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FLASH GENE
Symbol ZNF454 contributors: npt - updated : 03-03-2010
HGNC name zinc finger protein 454
HGNC id 21200
Location 5q35.3      Physical location : 178.368.193 - 178.393.218
Synonym symbol(s) FLJ37444, MGC138481
DNA
TYPE functioning gene
STRUCTURE 25.21 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 2300 - 522 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • twelve C2H2-type zinc fingers
  • one KRAB domain
    • HOMOLOGY
    interspecies homolog to murine Zfp454
    Homologene
    FAMILY
  • Krueppel C2H2-type zinc finger protein family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may be involved in transcriptional regulation
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • ion Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS