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FLASH GENE
Symbol GYG1 contributors: npt/ - updated : 12-04-2006
HGNC name glycogenin 1
HGNC id 4699
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP , PhosphoP
mono polymer homomer , dimer , complex
HOMOLOGY
interspecies homolog to murine Gyg
homolog to rattus Gyg1
Homologene
FAMILY
  • glycogenin family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    text colocalized with glycogen synthase
    basic FUNCTION
  • glycogenin glycosyltransferase activity
  • involved in the initiation reactions of glycogen synthesis, forming a protein primer for glycogen biosynthesis
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    glycogen biosynthesis
    a component
  • homodimer complexing with glycogen synthase
    • INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor,
  • Mn2+ is required for self glucosylation
    • protein
  • binding to GYG2
    • cell & other
    REGULATION
    Other self glycosylating protein
    up-regulated in muscle after prolonged exhaustive exercise, to facilitate rapid glycogen resynthesis
    inactivated with glycogen catabolism
    ASSOCIATED DISORDERS
    corresponding disease(s) GSD15
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS