Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol GYG1 contributors: npt/ - updated : 12-04-2006
HGNC name glycogenin 1
HGNC id 4699
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Digestiveliver    
Reproductivemale systemtestis  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP , PhosphoP
mono polymer homomer , dimer , complex
HOMOLOGY
interspecies homolog to murine Gyg
homolog to rattus Gyg1
Homologene
FAMILY
  • glycogenin family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic
    text colocalized with glycogen synthase
    basic FUNCTION
  • glycogenin glycosyltransferase activity
  • involved in the initiation reactions of glycogen synthesis, forming a protein primer for glycogen biosynthesis
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    glycogen biosynthesis
    a component
  • homodimer complexing with glycogen synthase
    • INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor,
  • Mn2+ is required for self glucosylation
    • protein
  • binding to GYG2
    • cell & other
    REGULATION
    Other self glycosylating protein
    up-regulated in muscle after prolonged exhaustive exercise, to facilitate rapid glycogen resynthesis
    inactivated with glycogen catabolism
    ASSOCIATED DISORDERS
    corresponding disease(s) GSD15
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS