basic FUNCTION
| inhibits PP1 enzymatic activity |
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PHACTR1 is likely to be a key regulator of endothelial cell function properties  |
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PHACTR1 is a key component in the angiogenic process  |
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PHACTR1 gene expression increases with the progression of calcification and regulation of PHACTR1 in SMCs modulates the severity of vascular calcification  |
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PHACTR1 takes part in neuronal functions regulated in a spatiotemporal manner  |
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PHACTR1 locus has also been involved in vascular hypertrophy in normal subjects, carotid dissection, migraine and coronary artery disease  |