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FLASH GENE
Symbol PHACTR1 contributors: - updated : 06-08-2004
HGNC name phosphatase and actin regulator 1
HGNC id 20990
Location 6p23      Physical location : 12.717.832 - 13.287.528
Synonym name RPEL repeat containing 1
Synonym symbol(s) KIAA1733, dJ257A7.2, RPEL1
DNA
TYPE functioning gene
STRUCTURE 569.00 kb     12 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
Endocrinepancreas   moderately
Lymphoid/Immunespleen   moderately
Nervousbrainbasal nucleicaudate nucleus highly
 brainlimbic systemhippocampus highly
 spinal cord   moderately
Reproductivefemale systemovary  moderately
 male systemtestis  lowly
Respiratorylung   moderately
Urinarykidney   moderately
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text brain (highly), liver (lowly)
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
three RPEL repeats
HOMOLOGY
interspecies homolog to murine Rpel1
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION
basic FUNCTION inhibits PP1 enzymatic activity
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein interacting with PP1 and actin
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS