Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

SDK1

contributors: mct - updated : 13-02-2008

HGNC name	sidekick homolog 1, cell adhesion molecule (chicken)
HGNC id	19307

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in glomeruli in HIV-associated nephropathy constitutional     --over   in podocytes is an important pathogenic factor in FSGS (Focal segmental glomerulosclerosis) and the mechanism involves disruption of the actin cytoskeleton possibly via alterations in MAGI1 function (MID: 20562105)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

mouse model of chronic FSGS that implicates the sdk-1 genetic pathway as important to the pathogenesis of glomerular sclerosis