Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | PSAT1 | contributors: mct - updated : 07-10-2014 |
HGNC name | phosphoserine aminotransferase 1 |
HGNC id | 19129 |
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Corresponding disease |
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Location | 9q21.31 Physical location : 80.912.058 - 80.945.007 | ||||
Synonym name | endometrial progesterone-induced protein | ||||
Synonym symbol(s) | PSA, EPIP, PSAT, MGC1460 | ||||
EC.number | 2.6.1.52 |
DNA |
TYPE | functioning gene |
STRUCTURE | 32.95 kb 9 Exon(s) |
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10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage | |
cell lines | highly in leukemia Jurkat, colon adenocarcinoma COLO2 320DM, hepatocellular carcinoma HepG2, weakly in leukemia MOLT3 ![]() |
fluid/secretion |
at STAGE |
cell cycle
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cell cycle, S |
PROTEIN |
PHYSICAL PROPERTIES |
STRUCTURE |
motifs/domains
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mono polymer | homomer , dimer |
HOMOLOGY |
interspecies | homolog to murine PSAT1 |
homolog to rattus LOC293820 |
Homologene |
FAMILY |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | extracellular |
| intracellular |
intracellular,cytoplasm,cytosolic |
basic FUNCTION | ![]() |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | aminoacid |
signaling |
three-enzyme serine biosynthesis pathway |
a component |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, |
protein | ![]() |
cell & other |
REGULATION |
Other | expression of mRNA is up-regulated during S phase |
ASSOCIATED DISORDERS |
corresponding disease(s) | PSATD , NELAS2 |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism | |
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Candidate gene | |
Marker | |
Therapy target | represents a new interesting target for colorectal cancer therapy ![]() |
ANIMAL & CELL MODELS |