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FLASH GENE
Symbol CUZD1 contributors: - updated : 03-03-2004
HGNC name CUB and zona pellucida-like domains 1
HGNC id 17937
Location 10q26.13      Physical location : 124.591.674 - 124.605.691
Synonym name estrogen regulated gene 1
Synonym symbol(s) ERG-1, UO-44
DNA
TYPE functioning gene
STRUCTURE 14.00 kb     12 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemuterus  highly
 female system   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelial    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text down-regulated in early pregnancy
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
CUB and zona pellucida domains, endoglin/CD105 antigen motif
HOMOLOGY
interspecies homolog to murine Itmap1
Homologene
FAMILY
CATEGORY unknown/unspecified
SUBCELLULAR LOCALIZATION     intracellular
basic FUNCTION plays an important role in events during the reproductive cycle and early pregnancy
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS reproduction/sex
PATHWAY
metabolism
signaling
a component transmembrane protein
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
induced by estrogen
inhibited by progesterone
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS