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FLASH GENE

Symbol

CUZD1

contributors: - updated : 03-03-2004

HGNC name	CUB and zona pellucida-like domains 1
HGNC id	17937

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	10q26.13      Physical location : 124.591.674 - 124.605.691
Synonym name	estrogen regulated gene 1
Synonym symbol(s)	ERG-1, UO-44

DNA

TYPE	functioning gene
STRUCTURE	14.00 kb     12 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive female system uterus     highly   female system       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

pregnancy

Text	down-regulated in early pregnancy

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

CUB and zona pellucida domains, endoglin/CD105 antigen motif

HOMOLOGY

interspecies

homolog to murine Itmap1

Homologene

FAMILY

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION

intracellular

basic FUNCTION

plays an important role in events during the reproductive cycle and early pregnancy

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

reproduction/sex

PATHWAY

metabolism

signaling

a component

transmembrane protein

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

induced by

estrogen

inhibited by

progesterone

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS