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FLASH GENE
Symbol CUZD1 contributors: - updated : 03-03-2004
HGNC name CUB and zona pellucida-like domains 1
HGNC id 17937
Location 10q26.13      Physical location : 124.591.674 - 124.605.691
Synonym name estrogen regulated gene 1
Synonym symbol(s) ERG-1, UO-44
DNA
TYPE functioning gene
STRUCTURE 14.00 kb     12 Exon(s)
MAPPING cloned Y linked N status provisional
Physical map
FGFR2 10q26 fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) ATE1 10q26.13 arginyltransferase 1 FLJ20003 10q26.13 hypothetical protein FLJ20003 TACC2 10q26 transforming, acidic coiled-coil containing protein 2 FLJ25359 10q26.13 hypothetical protein FLJ25359 PLEKHA1 10q26.3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 LOC387715 10 LOC387715 PRSS11 10q25.3-q26.2 protease, serine, 11 (IGF binding) LOC253436 10q26.13 hypothetical LOC253436 LOC390008 10 similar to hensin CUZD1 10q26.13 CUB and zona pellucida-like domains 1 MGC45962 10q26.13 hypothetical protein MGC45962 LOC118670 10q26.13 similar to hypothetical protein MGC45962 FLJ13490 10q26.13 hypothetical protein FLJ13490 MGC35392 10q26.13 hypothetical protein MGC35392 PEGASUS 10q26 zinc finger protein, subfamily 1A, 5 (Pegasus) ACADSB 10q25-q26 acyl-Coenzyme A dehydrogenase, short/branched chain LOC340784 10q26.13 similar to NK-type homeobox LOC387716 10 similar to Hmx2 protein LOC387717 10 LOC387717 BUB3 10q26 BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) LOC390009 10 similar to 40S ribosomal protein S26 GPR26 10q26.2-q26.3 G protein-coupled receptor 26 DKFZp761H2121 10q26.13 hypothetical protein DKFZp761H2121 LOC119587 10q26.13 hypothetical protein LOC119587 GALNAC4S-6ST 10q26 hypothetical protein LOC119587 FLJ12616 hypothetical protein FLJ12616 LOC340735 10q26.2 similar to germ cell specific Y-box binding protein; contrin OAT 10q26 ornithine aminotransferase (gyrate atrophy) OATL3 10q26 ornithine aminotransferase-like 3 (pseudogene) LOC390010 10 similar to Sax-1 LHPP 10q26.2 phospholysine phosphohistidine inorganic pyrophosphate phosphatase
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemuterus  highly
 female system   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelial    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text down-regulated in early pregnancy
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
CUB and zona pellucida domains, endoglin/CD105 antigen motif
HOMOLOGY
interspecies homolog to murine Itmap1
Homologene
FAMILY
CATEGORY unknown/unspecified
SUBCELLULAR LOCALIZATION     intracellular
basic FUNCTION plays an important role in events during the reproductive cycle and early pregnancy
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS reproduction/sex
PATHWAY
metabolism
signaling
a component transmembrane protein
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
induced by estrogen
inhibited by progesterone
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS