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FLASH GENE

Symbol

ZFP28

contributors: - updated : 08-07-2004

HGNC name	zinc finger protein 28 homolog (mouse)
HGNC id	17801

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive stomach         Reproductive female system breast mammary gland       male system testis       Urinary kidney         Visual eye

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective bone       Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	N-terminal signal peptide
	two KRAB domains
	14 C-terminal C2H2 zinc finger motifs

HOMOLOGY

Homologene

FAMILY

krüppel C2H2-type zinc-finger protein family

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION	involved in regulation of transcription, DNA-dependent
	may be playing a role in renal development and may also be involved in the repair of the kidney after ischemia- reperfusion or folic acid administration
	playing a role in embryonic development

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS