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FLASH GENE

Symbol

UCN

contributors: mct - updated : 07-12-2012

HGNC name	urocortin
HGNC id	12516

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   impaired endometrial expression of CRH and UCN mRNA in endometriosis constitutional     --over   plasma concentrations of UCN significantly increased in patients with HF (heart failure) and UCN may participate in the neurohumoral response of heart failure

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	for heart failure (plasma concentrations of UCN significantly increased in patients with heart failure)
Therapy target
	System Type Disorder Pubmed neurology neurodegenerative Parkinson/dementia Parkinsonism potential therapeutic implications in PD.

ANIMAL & CELL MODELS