| basic FUNCTION
| endogenous CRF-like factor in the brain responsible for the effects of stress on appetite |
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anti-inflammatory in gastric mucosa |
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involved in phosphorylation of mitogen-activated protein kinase (MAPK)-dependent pathway and activation of Ca2+-activated K+ channels |
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potent peptide inhibitor of feeding behavior, that can enter the brain from blood by leptin-facilitated permeation across the blood-brain barrier  |
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capable of maintaining adequate nigrostriatal function, via CRHR1 following a neuro-inflammatory challenge |
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may be a protective agent on endothelial function, benefiting endothelium by increasing endothelium-derived relaxing and decreasing contracting factors |
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inhibited the proliferation and promoted the apoptosis of endothelial cells and down-regulated VEGF expression via CRHR2 in hepatocellular carcinoma |
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might also be a double-edged sword because of its beneficial and detrimental influence to endothelium |
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produced during the development of MSCs to osteoblasts and differentially regulated during culture as well as by differentiation factors |
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cardioprotective and vasoactive peptide involved in cardiac regulation |
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role of urocortin in normal cardiovascular physiology and in the pathophysiology of heart failure |
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CRH and urocortin (UCN) are neuropeptides produced by human endometrium and modulate endometrial decidualization ( |
