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FLASH GENE

Symbol

NEGR1

contributors: mct - updated : 23-06-2020

HGNC name	neuronal growth regulator 1
HGNC id	17302

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to abnormal BMI and neurodevelopment in preschool-age children

Variant & Polymorphism other	cg23166710 was associated with both childhood phenotypes and correlated with NEGR1 placental expression

Candidate gene
Marker	increased level of NEGR1 in the frontal cortex may serve as molecular marker for a wider spectrum of psychiatric conditions
Therapy target

ANIMAL & CELL MODELS

Negr1 -/- mice had decreased adult hippocampal neurogenesis compared to wild-type mice