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FLASH GENE

Symbol

RRS1

contributors: SGE/npt - updated : 13-08-2009

HGNC name	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
HGNC id	17083

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	1.71 kb     1 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_015169 1 - 1724 NP_055984 - 365 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive female system uterus       Respiratory lung

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / hematopoietic bone marrow

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

arg/gly/lys-rich domain

HOMOLOGY

interspecies	homolog to murine Rrs1 (90.4pc)
	homolog to rattus Rrs1 (91.5pc)
	homolog to yeast Rrs1p

Homologene

FAMILY

RRS1 family

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,nucleolus
text	in nucleolus during interphase and distributed at the chromosome periphery during mitosis (Gambe 2009)

basic FUNCTION	may be implicated in the ribosome biogenesis regulation
	contributes to chromosome congression (Gambe 2009)

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS