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FLASH GENE
Symbol RRS1 contributors: SGE/npt - updated : 13-08-2009
HGNC name RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
HGNC id 17083
Location 8q13.1      Physical location : 67.341.262 - 67.342.966
Synonym name
  • homolog of yeast ribosome biogenesis regulator
  • ribosome biogenesis regulatory protein RRS1 homolog
  • Synonym symbol(s) KIAA0112
    DNA
    TYPE functioning gene
    STRUCTURE 1.71 kb     1 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 1724 - 365 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivefemale systemuterus   
    Respiratorylung    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • arg/gly/lys-rich domain
  • HOMOLOGY
    interspecies homolog to murine Rrs1 (90.4pc)
    homolog to rattus Rrs1 (91.5pc)
    homolog to yeast Rrs1p
    Homologene
    FAMILY
  • RRS1 family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleolus
    text
  • in nucleolus during interphase and distributed at the chromosome periphery during mitosis (Gambe 2009)
  • basic FUNCTION
  • may be implicated in the ribosome biogenesis regulation
  • contributes to chromosome congression (Gambe 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS