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FLASH GENE

Symbol

CREB5

contributors: - updated : 20-02-2004

HGNC name	cAMP responsive element binding protein 5
HGNC id	16844

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	bZIP transcription factor motif
	zinc finger C2H2 type

mono polymer

homomer , heteromer , dimer

HOMOLOGY

interspecies

homolog to murine Creb5

intraspecies

homolog to ATF2

Homologene

FAMILY

bZIP family, ATF subfamily

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION

transcriptional activator on binding to the cAMP responsive region (cre)

CELLULAR PROCESS

nucleotide, transcription

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA	binds DNA as a dimer and can form homodimer in the absence of DNA

RNA

small molecule

protein

can form an heterodimer with c-jun or ATF2

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS