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FLASH GENE
Symbol CREB5 contributors: - updated : 20-02-2004
HGNC name cAMP responsive element binding protein 5
HGNC id 16844
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemovary   
cell lineage
cell lines HelaS3, KATOIII, 253J
fluid/secretion
at STAGE
physiological period fetal, pregnancy
Text placenta, fetal brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • bZIP transcription factor motif
  • zinc finger C2H2 type
    • mono polymer homomer , heteromer , dimer
    HOMOLOGY
    interspecies homolog to murine Creb5
    intraspecies homolog to ATF2
    Homologene
    FAMILY bZIP family, ATF subfamily
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION transcriptional activator on binding to the cAMP responsive region (cre)
    CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binds DNA as a dimer and can form homodimer in the absence of DNA
    RNA
    small molecule
    protein can form an heterodimer with c-jun or ATF2
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS