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FLASH GENE

Symbol

PLEKHA4

contributors: mct - updated : 19-09-2018

HGNC name	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
HGNC id	14339

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_020904 20 - 3104 NP_065955 - 779 - 2000 11001876 NM_001161354 17 - 2808 NP_001154826 - 583 - 2000 11001876

EXPRESSION

Type	restricted

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart       lowly Digestive intestine small intestine     lowly   liver       lowly Urinary kidney       lowly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cells

System Cell Pubmed Species Stage Rna symbol Skin/Tegument melanocyte

cell lineage
cell lines	melanoma, highly
fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a pleckstrin homology (PH) domain
	a proline-rich domain

HOMOLOGY

Homologene

FAMILY

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,cytoplasm

basic FUNCTION

unknown

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	other,
	phosphatidylinositol binding

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS