Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

CCR4

contributors: mct - updated : 04-02-2015

HGNC name	chemokine (C-C motif) receptor 4
HGNC id	1605

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in skin and lymph nodes of adult T-cell leukemia tumoral     --other   aberrant expression of CCR4 in gastric cancer could contribute to tumor-induced immunosuppression constitutional     --over   in Parkinson disease (PD)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer digestive stomach downmodulation of CCR4 expression could be a promising immunotherapy for human gastric cancer allergy     blocking CCR4-ligand interaction may provide a novel therapeutic approach in allergic disease

ANIMAL & CELL MODELS