Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

TIA1

contributors: mct - updated : 29-08-2023

HGNC name	TIA1 cytotoxic granule-associated RNA binding protein
HGNC id	11802

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

ALS26 , WDM

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --other   expressed in synovium of patients with rheumatoid arthritis constitutional     --over   in the thyroid tissues in patients with Graves disease tumoral     --low   in hepatocellular carcinoma (HCC)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	TIA1 is a biomarker in HCC
Therapy target
	System Type Disorder Pubmed cancer digestive liver TIA1 is a therapeutic target in HCC

ANIMAL & CELL MODELS