protein
| UBOX5 |
|
ARIH1 interacts and co-localizes with UBE2L3 in mammalian cells, particularly in the perinuclear region |
|
both UBE2L3 and UBE2L6 bind to RNF19B |
|
interaction between the E3 ubiquitin ligase ITCH and the E2 UBE2L3 |
|
binding UBE3A |
|
UBE2N, UBE2L3 and UBE2D2/3 synergistically contribute to PRKN-mediated mitophagy |
|
MAP1B-LC1 (light chain) could interact with the ubiquitin-conjugating E2 enzyme UBE2L3 and the ubiquitination/degradation mechanism triggered by MAP1B-LC1 could be prevented by inhibiting the ubiquitin-proteasome proteolytic pathway |
|
NDFIP1 acts as an adaptor for UBE2L3 and ITCH |
|
controls IL1B secretion by inflammasomes |
|
CASP1, controls pyroptosis- and ubiquitin-independent proteasomal degradation of UBE2L3 upon canonical and non-canonical inflammasome activation by sterile danger signals and bacterial infection |
|
specifically protects CDKN1B from degradation |
|
UBE2L3 catalyzes the conjugation of heterotypic ubiquitin chains on CDKN1B that are proteolytically incompetent |