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| male mice lacking Wnt-7a fail to undergo regression of the Müllerian duct resulting of the absence of the receptor for Müllerian-inhibiting substance and Wnt7a-deficient females mice are infertile due to abnormal oviduct and uterus development  | |
double-mutant mouse lacking both WNT7A and the downstream scaffold protein Dishevelled display defect in the release of neurotransmitter and localization of synaptic proteins is affected |
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Wnt7a-Dvl1–deficient mice exhibit defects in spine morphogenesis and mossy fiber-CA3 synaptic transmission in the hippocampus |