| basic FUNCTION
| role in limb development and cell transformation  |
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plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function |
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implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis |
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controlling limb development at the dorsoventral axis |
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modulating cell fate and cell behavior during vertebrate development |
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upregulating LMX1A expression in limbs mesenchyme and dorsal differentiation |
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associated with cartilage destruction by regulating the maintenance of differentiation status and the apoptosis of articular chondrocytes via different mechanisms |
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playing a critical role in uterine smooth muscle pattering and maintenance of adult uterine function |
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involved in the development of the anterior-posterior axis in the female reproductive tract and in uterine smooth muscle pattering and maintenance of adult uterine function |
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capable of modulating aspects of neuronal plasticity |
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promoted the maturation of neural precursor cells into neurons |
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plays a role in cerebellar maturation |
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modulate the synaptic vesicle cycle and synaptic neurotransmission in mature hippocampal neurons |
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increases the clustering of synapsin 1 in granule cells |
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role in the regulation of organ-specific assembly and in the differentiation of the central nervous system vasculature |
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preferentially stimulates excitatory synapse formation and function |
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WNT7A signaling is critical to regulate spine growth and synaptic strength through the local activation of CAMK2 at dendritic spines |
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unique role in specifically promoting the formation and function of excitatory synapses in the hippocampus through the regulation of spine morphogenesis and synaptic strength |
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FN1 and WNT7A together regulate the homeostatic levels of satellite stem cells and satellite myogenic cells during regenerative myogenesis |
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WNT7A exercised critical control over multiple steps of neurogenesis by regulating genes involved in both cell cycle control and neuronal differentiation |
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WNT7A is a new regulator of ventral midbrain (VM) neurogenesis and dopaminergic (DA) axon growth and guidance |
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central role of the WNT7A-PAX6 axis in corneal epithelial cell fate determination |
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WNT7A induced cellular senescence via inactivation of S-phase kinase-associated protein 2, an important alternate regulator of cellular senescence |
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secreted glycoprotein that plays a critical role in tumorigenesis and development by controlling cell proliferation and differentiation |
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induces a unique phenotype of monocyte-derived macrophages with lower phagocytic capacity and differential expression of pro- and anti-inflammatory cytokines |
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has likely important role in tooth development and its mutation may lead to tooth agenesis, microdontia, and taurodontism |
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WNT7A and SFRP1 play likely opposite roles to ensure proper neural progenitors (NP) progeny in the developing cortex |
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hypoxia induced high expression of WNT7A might promote the cell migration via enhancing the epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma |
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WNT7A promotes the migration capacity of cancer cell |
