basic FUNCTION
| coupling with Gs alpha protein and activating adenylate cyclase |
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may be functioning as a neurotransmitter receptor |
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involvement in regulation of fear, anxiety, reproductive behaviors, release of pituitary hormones, and nociception |
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PTH2-PTH2R system involved in nociceptive information processing in the spinal cord, in the regulation of different hypophysiotropic neurons in the hypothalamus, and in the modulation of affective behaviors |
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possible new central mechanism for endocannabinoid regulation, via PTH2 acting on the PTH2R in discrete brain regions |
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role for PTH2R signaling in postnatal growth plate development and subsequent bone mass acquisition |
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PTH2, via its receptor, the parathyroid hormone 2 receptor (PTH2R), modulates fear memory |
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novel role for PTH2R signaling in extracellular matrix production |