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FLASH GENE
Symbol POLR2J contributors: - updated : 22-03-2006
HGNC name polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
HGNC id 9197
Location 7q11.2      Physical location : 102.113.547 - 102.119.381
Synonym symbol(s) RPB11, RPB11A, RPB11m, hRPB14, POLR2J1
EC.number 2.7.7.6
DNA
TYPE functioning gene
STRUCTURE 5.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
PLOD3 7q36 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 ZNHIT1 7q22.1 zinc finger, HIT domain containing 1 CLDN15 7q22 claudin 15 TTC11 7q22.1 tetratricopeptide repeat domain 11 LOC392082 7 similar to Zn-alpha-2-glycoprotein precursor FLJ14117 COL26A1 7q22.1 collagen, type XXVI, alpha 1 MYLC2PL 7q22.1 myosin light chain 2, precursor lymphocyte-specific CUTL1 7q22 cut-like 1, CCAAT displacement protein (Drosophila) APS 7q22 adaptor protein with pleckstrin homology and src homology 2 domains LOC392083 7 similar to Cohesin subunit SA-3 (Stromal antigen 3) (SCC3 homolog 3) LOC389542 7 similar to Williams-Beuren syndrome critical region protein 19 LOC389543 7 similar to postmeiotic segregation increased 2-like 9 LOC392084 7 similar to Cohesin subunit SA-3 (Stromal antigen 3) (SCC3 homolog 3) PRKRIP1 7q22.1 PRKR interacting protein 1 (IL11 inducible) C7orf19 7q22.1 chromosome 7 open reading frame 19 FLJ20013 7q22.1 hypothetical protein FLJ20013 DKFZp434K1815 7q22.1 hypothetical protein DKFZp434K1815 POLR2J 7q11.2 polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa HSPC047 7q22.1 HSPC047 protein RASA4 7q22-q31.1 RAS p21 protein activator 4 POLR2J2 7q11.22 polymerase (RNA) II (DNA directed) polypeptide J, related gene MGC35361 7q22.1 hypothetical protein MGC35361 MGC21636 LRRC17 7q22 leucine rich repeat containing 17 SVH 7q22.1 SVH protein NAPE-PLD 7q22.1 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D LOC392085 7 similar to 60S ribosomal protein L23a FLJ36166 7q22.1 hypothetical protein FLJ36166 LOC392086 7 similar to Putative S100 calcium-binding protein A11 pseudogene LOC389544 7 similar to hypothetical protein FLJ32949 PMPCB 7q21.3-q22.1 peptidase (mitochondrial processing) beta ZRF1 7q22.1-q22.3 zuotin related factor 1 PSMC2 7q22.1-q22.3 proteasome (prosome, macropain) 26S subunit, ATPase, 2 PRES 7q22.1 prestin (motor protein) RELN 7q22 reelin
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
RNA polymerase Rpb3/Rpb11 dimerization domain
mono polymer heteromer , dimer
HOMOLOGY
interspecies homolog to murine Polr2j
homolog to rattus LOC288588
intraspecies homolog to RASA4
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION subunit of RNA polymerase II, catalyzing the transcription of DNA into RNA
CELLULAR PROCESS nucleotide, transcription
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism purine/pyrimidine
signaling
a component
INTERACTION
DNA binding
RNA
small molecule
protein interacting with POLR2C
cell & other
REGULATION
repressed by doxorubicin treatment
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS