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FLASH GENE
Symbol ZNF8 contributors: - updated : 25-07-2006
HGNC name zinc finger protein 8 (clone HF.18)
HGNC id 13154
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue  highly
Lymphoid/Immunethymus   highly
Respiratoryrespiratory tractlarynx  highly
cell lineage
cell lines ubiquitously present in many human cell lines of different embryological derivation
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 7 C2H2-type zinc fingers
  • a KRAB domain
    • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY zinc finger protein family, C2H2 type, Krüppel-like
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION may be involved in transcriptional regulation
    CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    zinc Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS