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FLASH GENE
Symbol ZNF8 contributors: - updated : 25-07-2006
HGNC name zinc finger protein 8 (clone HF.18)
HGNC id 13154
Location 19q13.43      Physical location : 58.790.317 - 58.807.254
Synonym symbol(s) ZFP18, HF.18
DNA
TYPE functioning gene
STRUCTURE 16.00 kb     4 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue  highly
Lymphoid/Immunethymus   highly
Respiratoryrespiratory tractlarynx  highly
cell lineage
cell lines ubiquitously present in many human cell lines of different embryological derivation
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 7 C2H2-type zinc fingers
  • a KRAB domain
    • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY zinc finger protein family, C2H2 type, Krüppel-like
    CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION may be involved in transcriptional regulation
    CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
    zinc Zn2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS