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FLASH GENE
Symbol IGHA2 contributors: np/ - updated : 22-11-2005
HGNC name immunoglobulin heavy constant alpha 2 (A2m marker)
HGNC id 5479
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
CATEGORY immunity/defense
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • may be serving both to defend against local infection and to prevent access of foreign antigens to the general immunologic system
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
  • forming an homodimer of two D heavy chains bound by an unique disulfide bond
  • each heavy chain is bound to a light chain (kappa or lambda)
  • the N terminus of the heavy chain is bound to a V segment
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS