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FLASH GENE
Symbol TUBA4A contributors: - updated : 31-08-2007
HGNC name tubulin, alpha 4a
HGNC id 12407
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer heteromer , dimer
HOMOLOGY
interspecies homolog to C.elegans tba-2
ortholog to rattus tuba4 (92 pc)
Homologene
FAMILY tubulin superfamily composed of six distinct families
CATEGORY structural protein
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton,microtubule
basic FUNCTION
  • major components of microtubules, having a GTPase activity
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component heterodimer of alpha and beta tubulin
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
  • binds two moles of GTP, one at an
    • exchangeable site on the beta chain and one at a nonexchangeable site on the alpha-chain
    protein
  • GRM7
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS