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FLASH GENE
Symbol ERAS contributors: - updated : 29-03-2004
HGNC name ES cell expressed Ras
HGNC id 5174
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Eras
Homologene
FAMILY Ras GTPase superfamily
CATEGORY enzyme , protooncogene
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • constitutively active
  • GTPase activity, important in the tumor-like growth properties of embryonic stem cells
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism energetic
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule nucleotide,
    GTP binding
    protein interacts with PI3 hydroxygenase
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS