Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol HMX3 contributors: mct/npt - updated : 11-04-2008
HGNC name H6 family homeobox 3
HGNC id 5019
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivesalivary gland    
Reproductivefemale systemovary   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text expressed in the craniofacial region of developing embryos
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • HMX homeobox family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • may be functioning redundantly to control embryonic development of the central nervous system
  • have a role in sensorineural hearing (Miller 2009)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene for human inner ear vestibular development and a role in sensorineural hearing observed in del 10q26 patients (Miller 2009)
    Marker
    Therapy target
    ANIMAL & CELL MODELS
    hmx2/hmx3 knockout mice have vestibular anomalies