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FLASH GENE

Symbol

GNPDA1

contributors: - updated : 03-05-2004

HGNC name	glucosamine-6-phosphate deaminase 1
HGNC id	4417

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol blood / hematopoietic spleen         Endocrine pancreas islet of Langerhans       Nervous brain diencephalon hypothalamus   highly Reproductive female system ovary         female system uterus         male system testis     highly Skin/Tegument skin         Urinary kidney       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / Hematopoietic bone marrow       Lymphoid

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

pregnancy

Text	fetal_spleen, brain, kidney, heart, liver

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

mono polymer

hexamer

HOMOLOGY

interspecies	homolog to murine Gnpda1
	homolog to hamster oscillin

intraspecies

homolog to GNPDA2

Homologene

FAMILY

glucosamine/galactosamine-6 phosphate isomerase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytosolic

basic FUNCTION	catalyzes the reversible conversion of D-glucosamine-6-phosphate (GlcN6P) into D-fructose-6-phosphate (Fru6P) and ammonium
	may be playing an essential role for egg activation and early embryo development

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

reproduction/sex

PATHWAY

metabolism

carbohydrate , energetic

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS