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FLASH GENE

Symbol

TOP1

contributors: mct - updated : 30-11-2015

HGNC name	topoisomerase (DNA) I
HGNC id	11986

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral fusion       fused with NUP98 in t(11;20)(p15;q11) in therapy related myelodysplastic syndrome tumoral   amplification     is associated with advanced tumours and poor prognosis in melanoma

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS