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FLASH GENE
Symbol SLC39A7 contributors: mct - updated : 12-11-2021
HGNC name solute carrier family 39 (zinc transporter), member 7
HGNC id 4927
ASSOCIATED DISORDERS
corresponding disease(s) AGM9
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional       loss of function
resulted in augmented ER stress and impaired receptor trafficking, thereby globally affecting downstream signaling
Susceptibility
Variant & Polymorphism
Candidate gene might be a novel target for diseases such as cancer where prevention of tyrosine kinase activation would be therapeutically advantageous (Hogstrand 2009)
Marker
Therapy target
ANIMAL & CELL MODELS