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FLASH GENE
Symbol SLCO5A1 contributors: mct - updated : 03-10-2019
HGNC name solute carrier organic anion transporter family, member 5A1
HGNC id 19046
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • 12 transmembrane domains
    • HOMOLOGY
    Homologene
    FAMILY
  • solute carrier organic anion transporter superfamily
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    text
  • SLCO5A1 and SLCO3A1 localized to the plasma membrane of epithelial cells of the lactiferous ducts in normal breast tissue
    • basic FUNCTION
  • mediating the Na(+)-independent transport of organic anions
  • might be a non-classical OATP family member which is involved in biological processes that require the reorganization of the cell shape, such as differentiation and migration
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) DEL8q13
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
  • might be novel biomarker for tumor progression and the development of metastasis in small cell lung cancer (SCLC) patients
    • Therapy target
    ANIMAL & CELL MODELS