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FLASH GENE

Symbol

TMEM5

contributors: mct - updated : 16-01-2013

HGNC name	transmembrane protein 5
HGNC id	13530

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a glycosyltransferase domain
	a signal anchor for a type II membrane protein encoded by AAs 10–30
	a cytoplasmic domain encoded by AAs 1–9
	a domain that has some similarities to exostosin (AAs 218–353), which is a domain found in EXT1
	an extracellular domain encoded by AAs 31–443

HOMOLOGY

Homologene

FAMILY

TMEM5 family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,cytoplasm
text	type 2 transmembrane protein

basic FUNCTION

transmembrane protein with a potential glycosyltransferase function

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

WLKWS8

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS