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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

S100A12

contributors: mct - updated : 02-06-2017

HGNC name	S100 calcium binding protein A12 (calgranulin C)
HGNC id	10489

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   in inflammatory bowel disease constitutional     --over   during the acute stage of Kawasaki disease

Susceptibility

to rheumatoid arhritis psoriasis

Variant & Polymorphism

Candidate gene
Marker	mRNA expression of S100A12 and AGER might be as a useful biomarker for Transitional cell carcinoma (TCC)
	regular measurements of fecal S100A12 levels reliably detect inflammatory bowel disease relapse at an early stage, which makes the test a promising noninvasive tool for monitoring and optimizing therapy
Therapy target

ANIMAL & CELL MODELS