Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol POLR1D contributors: npt/mct - updated : 05-07-2017
HGNC name polymerase (RNA) 1 polypeptide D, 16kDa
HGNC id 20422
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated PhosphoP
HOMOLOGY
interspecies ortholog to yeasrAC40
Homologene
FAMILY
  • archaeal rpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleolus
    basic FUNCTION
  • biosynthesis ot rRNA
  • may play a role for the kidney aging (Wheeler 2009)
    • CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism purine/pyrimidine
    signaling
    a component
  • component of the multisubunit complex of eukaryotic nuclear RNA polymerase producing ribosomal RNA
  • binding to ribosomal genes in association with the C subunit
    • INTERACTION
    DNA binding
    RNA
    small molecule
    protein interacting with MAF1 (MAF1 is a major regulator of pol III and POLR1D transcription in human cells) (Reina 2006)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) TCSPD
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS