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Symbol NUDT14 contributors: - updated : 13-11-2006
HGNC name nudix (nucleoside diphosphate linked moiety X)-type motif 14
HGNC id 20141
Location 14q32.33      Physical location : 105.639.276 - 105.647.660
Synonym name
  • nudix motif 14
  • uridine diphosphate glucose pyrophosphatase
  • UDP-sugar diphosphatase
  • Synonym symbol(s) UGPP
    EC.number 3.6.1.45
    DNA
    TYPE anonymous DNA segment
    STRUCTURE 8.00 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Endocrinepancreas    
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Epithelialsecretoryglandularendocrine 
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    NUDIX domain
    mono polymer homomer , dimer
    HOMOLOGY
    interspecies homolog to murine Nudt14
    Homologene
    FAMILY Nudix hydrolase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION cleaving the pyrophosphate bond of UDP-glucose
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
    Mg2+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS