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FLASH GENE
Symbol DPP10 contributors: mlc - updated : 24-11-2007
HGNC name dipeptidylpeptidase 10
HGNC id 20823
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
interspecies ortholog to murine Dpp10
ortholog to ratus Dpp10_predicted
intraspecies homolog to DPP6
Homologene
FAMILY
  • peptidase family S9B
  • dipeptidyl peptidase IV (DPIV) gene family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • cleaving terminal dipeptides from cytokines and chemokines, and presents a potential new target for asthma therapy
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binds KCND2, KCND1
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    asthma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS