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FLASH GENE
Symbol DPP10 contributors: mlc - updated : 24-11-2007
HGNC name dipeptidylpeptidase 10
HGNC id 20823
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbraindiencephalonamygdala  
nervousbrainbasal nuclei   
Nervousbraindiencephalonthalamus  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
interspecies ortholog to murine Dpp10
ortholog to ratus Dpp10_predicted
intraspecies homolog to DPP6
Homologene
FAMILY
  • peptidase family S9B
  • dipeptidyl peptidase IV (DPIV) gene family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • cleaving terminal dipeptides from cytokines and chemokines, and presents a potential new target for asthma therapy
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binds KCND2, KCND1
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    constitutional        
    asthma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS