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FLASH GENE
Symbol TMEM132A contributors: mct - updated : 29-03-2022
HGNC name transmembrane protein 132A
HGNC id 31092
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • extra-cellular portions contain five conserved domains including three tandem immunoglobulin domains, and a cohesin domain homologue
    • HOMOLOGY
    interspecies ortholog to TMEM132A TMEM132A
    ortholog to murine Tmem132a
    Homologene
    FAMILY
    CATEGORY immunity/defense
    SUBCELLULAR LOCALIZATION extracellular
        plasma membrane
    basic FUNCTION
  • playing a functional role in embryonic and postnatal development of the brain
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • TMEM132A, TMEM132B, TMEM132C, TMEM132D may regulate NCKAP1 in WAVE regulatory complex (WRC) to finely modulate actin nucleation, cellular cytoskeletal and morphological changes
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS